Mammalian ORFs
HORIZON DISCOVERY BIOSCIENCES LIMITED ORFEOME COLLAB. MM GABBR2 ORF
NC2603667 ORFEOME COLLAB. MM GABBR2 ORF
OriGene LENTI ORF PARTICLES, ALPPL2
Lenti ORF particles, ALPPL2 (Myc-DDK tagged) - Human alkalinephosphatase, placental-like 2 (ALPPL2), 200ul, >10^7 TU/mL(200
ABclonal Technology p-LATS1-T1079-LATS2-T1041
The protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis The protein is phosphorylated in a cell-cycle dependent manner with late prophase phosphorylation remaining through metaphase The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative regulator of CDC2 cyclin A In addition the C-terminal kinase domain binds to its own N-terminal region suggesting potential negative regulation through interference with complex formation via intramolecular binding Biochemical and genetic data suggest a role as a tumor suppressor This is supported by studies in knockout mice showing development of soft-tissue sarcomas ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments
ABclonal Technology KO Validated NRF2 Rabbit mAb
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals Multiple transcript variants encoding different isoforms have been characterized for this gene
Sino Biological Human Glypican 3/GPC3/OCI-5 Gene ORF cDNA clone expression plasmid, C-His tag 1Unit
Full length Clone DNA of Human glypican 3 with C terminal His tag.